Gut worms may hinder cholera vaccine

时间:2019-03-01 05:07:03166网络整理admin

VACCINES against cholera may not work in people who have worms. Cholera vaccines have had limited success: in 2000, a promising vaccine made from live, weakened cholera bacteria protected 80 per cent of the North American or European adults who took it, but a much smaller proportion of Indonesians, with protection levels especially low in children. One explanation was that intestinal worms, which infect around 80 per cent of children in poor tropical countries, might change the body’s immune responses. To investigate, scientists at the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh,